The term pharmacokintics refers to the actions taken by the human body to absorb, distribute, metabolize, and eliminate a medication. Pharmacodynamics refers to the actions of the drug on the body tissues and cells to obtain the desirable effect. This article explains various routes of administration of drugs into the body, factors influencing distribution, and methods of drug metabolism and elimination.
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The elderly are the fastest growing segment of the population and their health-related issues are a significant concern to the medical community. Normal physiological changes occur in an aging body, making it significantly different from the younger counterpart. These changes involve various organs and tissues, including the heart, liver, kidneys, gastrointestinal system, and muscle. As a result of these age-related changes, some medications may affect the aging body differently than the younger one. Given that fact, the elderly are at a significant risk of drug toxicity or diminished drug action if special care is not taken to compensate for the changes of the aging body.